Regional BC BC 546 years Persia was ruled until 334. During this period, an important commercial center of Sardis. BC Passing through Thrace to Anatolia in 334, Alexander the Great, the Persians defeated the armies advanced towards Syria and put an end to the sovereignty of Persia. BC Alexander the Great Satrapies struggle with each other after the death in 323 BC Empire of Alexander the Great in 301 the end of the period, the most important works getirmiştir.Bu Örenyeri'ndeki Sardis Temple of Artemis.
Regaip-Fitr from October 25-26 on the night of 1313, which corresponds Manisa Alpage Saruhan Bey's son and was conquered by the soldiers under the command center was transformed into the principality of Saruhanoguls. Saruhan Bey's tomb in the center of the city, who died in 1346. Ilyas Bey's son instead of before, and the principality of his death was the most glorious periods Ishak Bey Çelebi had survived. Ulu Mosque and Medrese, the Mevlevi, and numerous works, such as pit Hammam Ishak Çelebi brought to the city. Presumably, towards the year 1390 had died and was buried in his tomb built.